Methemoglobinemia occurs when the ferrous (Fe2+) form of iron in hemoglobin is oxidized to the ferric (Fe3+) form and cannot bind O2. What are the clinical manifestations of methemoglobinemia?

Methemoglobinemia occurs when the ferrous (Fe2+) form of iron in hemoglobin is oxidized to the ferric (Fe3+) form and cannot bind O2. What are the clinical manifestations of methemoglobinemia?



Answer: Dyspnea, headaches, dizziness, altered mental status with cyanosis of extremities, and darkened blood. Treat with methylene blue.



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