What other tests are used to determine the presence of a capsule? How do the tests work?

What other tests are used to determine the presence of a capsule? How do the tests work?



Answer: Latex agglutination. Latex beads complexed to antibodies precipitate when they bind the capsular antigen of interest. This test is usually used to aid in diagnosis of bacterial meningitis. Wet mount with India ink also can be used to identify Cryptococcus capsule.



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