What is the mechanism of action of macrolide (erythromycin, azithromycin, clarithromycin) antibiotics?

What is the mechanism of action of macrolide (erythromycin, azithromycin, clarithromycin) antibiotics?



Answer: They bind to the 50S ribosomal subunit and prevent the translocation step in protein synthesis.


Mnemonic:

Macrolide stops the slide


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