Cycloserine is a second-line agent for tuberculosis. What is the mechanism of action of cycloserine? What are its side effects?
Answer: Analog of D-alanine that prevents the formation of the D-alanyl-D-alanine dipeptide in cell wall synthesis. CNS toxicity: seizures, acute psychosis, and peripheral neuropathy
Mnemonic:
PSYCHO-serine due to CNS side effects
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