What are the potential problems with cephalosporins that contain N-methyl-thiotetrazole side chains?

What are the potential problems with cephalosporins that contain N-methyl-thiotetrazole side chains?



Answer: Disulfiram-like reaction causing hypotension, nausea, and vomiting when ingested with ethanol and prolonged prothrombin time because of interference with vitamin K activity leading to increased risk of bleeds


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