What is a live-attenuated vaccine?Answer: Attenuated vaccine has microbe with selective deletions of genes involved in pathogenesis. Organisms replicate...
Methemoglobinemia occurs when the ferrous (Fe2+) form of iron in hemoglobin is oxidized to the ferric (Fe3+) form and cannot bind O2. What are the clinical manifestations of methemoglobinemia?
Methemoglobinemia occurs when the ferrous (Fe2+) form of iron in hemoglobin is oxidized to the ferric (Fe3+) form and cannot bind O2. What are the clinical...
Which antibiotic is a PABA analog with a side effect profile that includes hemolysis and methemoglobinemia?
Which antibiotic is a PABA analog with a side effect profile that includes hemolysis and methemoglobinemia?Answer: Daps...
Name the three drugs commonly used in the treatment of leprosy:
Name the three drugs commonly used in the treatment of leprosy:1. Dapsone2. Rifampin3. Clofazim...
What are important side effects of INH?
What are important side effects of INH?Answer: Hepatotoxicity (avoid alcohol), peripheral neuropathy (vitamin B6 depletion), sideroblastic anemia...
What is the mechanism of action for INH?
What is the mechanism of action for INH?Answer: Although not proven, it is thought to inhibit mycolic acid synthe...
What are some common side effects of rifampin?
What are some common side effects of rifampin?Answer: Red-orange urine, induces P450 potentially leading to impaired efficacy of other drugs, GI...
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